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However, when ROS levels rise beyond the capacity of antioxidants, they can damage cellular macromolecules, disrupt normal cell functions, trigger mitochondria to produce pro-apoptotic proteins, and ultimately lead to the apoptosis of central nervous system neurons (Schieber and Chandel, 2014)

BACKGROUND.l-Carnitine, an abundant nutrient in red meat, accelerates atherosclerosis in mice via gut microbiotadependent formation of trimethylamine (TMA) and trimethylamine N-oxide (TMAO) via a multistep pathway involving an atherogenic intermediate, -butyrobetaine (BB)

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Reconstitution techniques

For example, some gut microbes have the ability to remove iodine atoms in hormones, which may lead to the inhibition of the synthesis and secretion of thyroid hormones (Khrle et al., 1987)

Jauniaux E, Watson AL, Hempstock J, Bao YP, Skepper JN, Burton GJ: Onset of maternal arterial blood flow and placental oxidative stress