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Akhter Hossain at the University of Melbourne in Australia has suggested rather than adding a fatty acid side chain, a glycan group may work instead which is more hydrophilic and therefore easier to dissolve and purify

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Technologies surrounding constrained peptides, developed by various biotech firms, are increasingly attracting interest from larger pharmaceutical companies

Specifically, LGP2 can negatively regulate RIG-I-mediated recognition of viral dsRNA, thereby reducing the production of IFN-I and other inflammatory mediators and leading to the suppression of antiviral responses (41)