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GLP-1 receptor agonists have been used successfully and safely in type 2 diabetes mellitus (T2DM) and do not induce insulin desensitization after prolonged use, as they do not activate insulin receptors in normoglycemic subjects [16] and thus do not cause hypoglycemia

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Statements from the FDA About Ozempic On October 2, 2024, the FDA issued a postmarket safety information statement about concerns with unapproved versions of GLP-1 receptor agonists used for weight loss

Like Wegovy, Ozempic should not be used if its previously been frozen

doi: 10.1038/s41598-020-58872-0 131 SunG.HuC.MeiQ.LuoM.ChenX.LiZ.et al

In type 2 diabetes mellitus ( T2DM ), there is a decreased responsiveness of tissues to insulin, known as insulin resistance