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Steliou K, Faller DV, Pinkert CA, Irwin MH, Moos WH

LIPO-C subcutaneous versus intramuscular injection routes differ fundamentally in three areas: absorption speed, injection site tolerance, and the practical feasibility of patient self-administration outside clinical supervision

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doi:10.3389/fmed.2022.914356 Naeini F, Tanha FD, Mahmoudi M, Ansar H, Hosseinzadeh-Attar MJ

Am J Med 2018;131:443.e11-24.ArticlePubMed 977

It may help restore the muscle architecture and vascular density needed to handle normal exertion though patients with PEM should approach any intervention with careful pacing and clinical oversight