73 Bempedoic Acid On February 21st, 2020, the Food and Drug Administration (FDA) approved bempedoic acid (Nexletol), an oral, non-statin medication taken once daily as an adjuvant to statin therapy to further lower LDL cholesterol levels
In parallel, excessive Cu + generated in GSH-rich reductive environments can bind lipoylated mitochondrial TCA-cycle proteins such as DLAT, inducing aberrant protein aggregation and triggering cuproptosis across multiple cancer types 187,189,192-194
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