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Given that several important muscles cross the ankle joint, this research suggests benefits for injuries affecting these transition zones

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Consequently, this could improve cellular function by regulating cellular events, such as cytokine production, cell proliferation, synthesis of DNA and proteins, etc

It can also help reduce exercise-induced stress, minimize muscle pain, and enhance recovery

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The research experiment employed in vitro models of microglia and nerve injury (including zebrafish in vivo experiments, cerebral ischemia rat models, neuronal injury models, Alzheimers disease 5xFAD mouse models, and spinal cord injury rat models)