Appetite suppression may lessen after medication is discontinued, and some patients regain part of the weight they previously lost
Intense exercise, environmental pollutants, and high-stress periods can deplete your stores faster than your body can replenish them
Abbreviations ASCVD: Atherosclerotic cardiovascular disease BMI: Body mass index CI: Confidence interval CKD: Chronic kidney disease CVD: Cardiovascular disease eGFR: Estimated glomerular filtration ratio GLP-1RA: Glucagon-like peptide-1 receptor agonist HFpEF: Heart failure with preserved ejection fraction HFrEF: Heart failure with reduced ejection fraction HHF: Heart failure hospitalization HR: Hazard ratio LDL: Low-density lipoprotein LVEF: Left ventricular ejection fraction MACE: Major cardiovascular events MRA: Mineralocorticoid receptor antagonist SGLT2: Sodium-glucose cotransporter 2 References Wong ND, Sattar N
These include decreased sperm count, reduced muscle or bone mass, accumulated body fat, and erectile dysfunction
Ghrelin agonist ipamorelin effects on the HPT axis
Understanding these limitations helps set realistic expectations and encourages more cautious decision-making, which ultimately reduces risk