So these GLP-1s basically mimic a hormone in the body that controls insulin and blood glucose levels, which can make a patient feel less hungry or feel full for longer
Risk of Scarring Inflammatory acne can increase your risk of developing scarring, especially if breakouts are severe or long-lasting
GLP-1 has several important functions (Mozzafariun et al 2025): Slows stomach emptying, helping you feel fuller longer Stimulates insulin release and helps lower blood sugar after meals Reduces appetite and food intake giving you a clear stop eating signal
SMC Chair Dr Rob Peel said: "Semaglutide will provide a useful treatment option to help reduce major cardiovascular events in patients who are overweight and have cardiovascular disease." Speaking after the announcement, Sebnem Avsar Tuna, General Manager Novo Nordisk UK said: We are delighted that the SMC has recognised the value semaglutide can bring to the people in Scotland who are living with established cardiovascular disease and overweight or obesity, where the threat of a secondary event is a constant reality
The fear isn't hypothetical as Bernard points to a pattern the industry has seen before
How clinicians approach this issue During regular reviews, NHS teams routinely ask about injection-site reactions