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Safety outcomes (adverse events) were synthesized descriptively because AE reporting was incomplete and not sufficiently consistent across trials to support quantitative synthesis

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The SURPASS clinical trials have highlighted its significant A1C lowering and weight loss benefits, marking it as a promising option for patients with diabetes and obesity

It acts as a shuttle for long-chain fatty acids, facilitating their entry in the mitochondrial matrix for lipid -oxidation and the subsequent production of energy 2