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[DOI] [PMC free article] [PubMed] [Google Scholar] 88.Samms R.J., Coghlan M.P., Sloop K.W

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Like Semaglutide, Tirzepatide was initially designed to treat type 2 diabetes by mimicking two key hormones: GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide)

Lack of modulation by short-term fasting and some other ingestive peptides that may interact with GLP-1, including leptin, glucagon, insulin, neuropeptide Y, and melanin-concentrating hormone

Monjauro Mounjaro, FDA-approved in 2022 for the treatment of type 2 diabetes, is one of Eli Lillys most widely discussed drugs due to its reported weight loss benefits