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DERMAL MELANOCYTOSIS Whereas in normal skin only melanocytes in the epidermis and hair follicles produce melanin, dermal melanocytosis is characterized by the presence of dermal melanocytes that actively synthesize melanin

doi: 10.1111/exd.12409 195 ItohMSuganamiTNakagawaNTanakaMYamamotoYKameiYet al

RAAS inhibitors are cornerstone therapies for hypertension, heart failure, and post-myocardial infarction, with both systemic and local cardiac effects contributing to inflammation and fibrosis

The combined treatment had the most pronounced neuroprotective effect against hippocampal inflammation, tau accumulation, and neural apoptosis

Only one study did not identify any benefit of GLP-1RAs in animal models of opiate misuse, although this same study had shown a positive effect for alcohol misuse 63

68 , e2300286 (2024)