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A study in Frontiers in Endocrinology found that tesofensine positively impacts metabolism, improving insulin sensitivity and energy levels, especially in patients with obesity

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The STEP 8 trial: direct comparison The STEP 8 trial is the most important study for this comparison because it pitted semaglutide 2.4 mg weekly directly against liraglutide 3.0 mg daily in adults with overweight or obesity but without diabetes

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