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122, no

J Am Pharm Assoc (2003)

Continuous GLP-1RA use for three years was associated with the greatest reduction in MACE risk compared with sulfonylureas, whereas interruptions and discontinuations were associated with a progressive attenuation of this protective effect, with risk estimates in some scenarios approaching those of the comparator group

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"To minimize brain fog and mood changes, we recommend staying well hydrated, eating protein early in the day, and keeping a consistent sleep routine." And managing common GLP-1 side effects like nausea and constipation often comes down to small, daily habits: "For nausea, eat slowly, avoid greasy or rich foods, and consider starting your day with bland, high-protein meals like eggs or Greek yogurt," says Dr