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BIOLOGICAL ACTIVITIES The two known IGF factors were isolated initially as serum factors with insulin-like activities that could not be neutralized by antibodies directed against insulin

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Figure 2 Adult zebrafish and mammals have been exposed to a hypoxic environment during embryonic life, and the heart has a strong regenerative capacity (37), and oxidative phosphorylation produces 18 times more ATP than cytoplasmic glycolysis (38), which is one of the factors that induce cardiomyocytes to exit the cell cycle

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