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Common Side Effects Injection site redness and mild irritation (resolves in hours) Mild nausea with oral peptides on an empty stomach Temporary fatigue during the first week, particularly with TB-500 Healing flare: old injuries may temporarily ache as repair processes activate Serious Safety Considerations FDA regulatory status

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Innovations in delivery systems, 459,460 such as myocardium-targeted LNPs and intelligent, responsive nanocarriers, promise to improve cardiac-specific delivery of RNA and protein therapies