Persistent stimuli, such as chronic inflammation, lead to excessive collagen accumulation and fibrosis progression 38
Accumulation of senescent cells during aging increases the adipocyte death rate Approximately 10% of the total fat cell pool is renewed annually in adulthood by adipocyte death and ongoing adipogenesis independent of the body mass index [31], which is referred to as adipocyte turnover [32]
found that efficacy was consistent across mRNA, DNA, viral vectors, and inactive viruses and that differences in trial design, population characteristics and other factors were stronger contributors to heterogeneity than vaccine modality
Glia 22:1118 Krejsa CM, Franklin CC, White CC, Ledbetter JA, Schieven GL, Kavanagh TJ (2010) Rapid activation of glutamate cysteine ligase following oxidative stress
Metabolic effects of a carnitine-free diet fed to college students
Cancer Res, 2002