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NICE technology appraisal TA875 (semaglutide for managing overweight and obesity) provides the current UK framework for licensed incretin-based weight management and focuses on metabolic and cardiovascular outcomes

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Chronic low-grade inflammation (inflammaging) is increasingly recognized as a driver of age-related disease, and BPC-157s ability to modulate inflammatory pathways may have broader implications for healthy aging

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In the REDEFINE 1 trial, only 1% of participants discontinued treatment due to adverse events

[DOI] [PubMed] [Google Scholar] 132.Voshol PJ, Haemmerle G, Ouwens DM, Zimmermann R, Zechner R, et al