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In addition to metabolizing bilirubin and certain anti-cancer drugs in the liver, the alpha class of these enzymes exhibit glutathione peroxidase activity, thereby protecting the cells from reactive oxygen species and the products of peroxidation

Rizzo A, Santoni M, Mollica V, Logullo F, Rosellini M, Marchetti A, et al

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Fights oxidative stress: Collagen acts as an antioxidant, combating free radicals that can damage hair follicles

Skin samples were fixed with 4% paraformaldehyde, embedded in paraffin, and sectioned for H&E, Masson, and immunohistochemical staining

In a separate head-to-head comparison, GHK-Cu outperformed both retinol (vitamin A) and vitamin C in improving skin firmness and elasticity, and it did so without the irritation, photosensitivity, or adjustment period associated with retinoid use