glp-1 and gip/glp-1 receptor agonists Possible mechanisms of the interaction of GIP for treatment The Effects of Dual GLP-1/GIP

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Because their mechanisms are complementary rather than overlapping

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Studies have shown that variations in the GIPR gene are linked to cardiovascular disease and metabolic syndrome characteristics, which supports this idea [110]

(Dalian, China)

These results show that GLP-1RA can induce phosphorylated AMPK expression (91), inhibit the expression and phosphorylation of the mTOR protein (92), promote the apoptosis of endometrial cancer cells, and thus play a potential anticancer role