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301.1 What anchor correlation value should I use when deriving Meaningful Within Patient Change (MWPC) values Alexander Hind 1 , Mike Greenwood 1 , Kim Cocks 1 1 Adelphi Values, Manchester, UK Journal of Patient-Reported Outcomes 2026 , 10(Suppl 1) :301.1 Aims Anchor-based analyses are routinely used to derive MWPC thresholds for Clinical Outcome Assessments (COAs) for use in clinical trials

The FDA has also clarified that products applied to the skin rather than ingested do not meet the regulatory definition of dietary supplements

That raises the prospect, she said, that patients will stop taking the drugs and regain weight, which will lead to "poor clinical outcomes."

Both cause similar side effects, primarily gastrointestinal issues like nausea, diarrhea, and constipation

Septerna Sector: GPC Septerna R-targeted oral small molecule drug discovery, including GLP-1, GIP, and glucagon receptors HQ: South San Francisco, CA Year Founded: 2019 (under the name GPCR NewCo, Inc.)

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