Second, this analysis focused exclusively on a subset of GLP-1 RA therapies (specifically semaglutide and tirzepatide) and did not account for other common PCOS treatments, such as metformin, combined oral contraceptives, or anti-androgen therapies
Read in context, it is a secondary, exploratory outcome from a Phase 2 trial whose primary endpoint, change in cerebral glucose metabolism, was negative, and whose cognitive signal was modest
That sugar gets digested and turns into glucose, which raises your blood sugar levels
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However, GLP-1-R agonists may be considered when the aforementioned are contraindicated or not tolerated [6]
Taking more than prescribed within a 24-hour period can lead to severe side effects, most notably dangerously low blood sugar levels, particularly if youre also on insulin