doi: 10.3389/fcimb.2024.1470808 154 ZllerBSundquistJSundquistKOhlssonH
& Raff, M
Synthesis of (((ethane-1,2-diylbis(azanediyl))bis(carbonyl))bis(4,1-phenylene))diboronic acid(EBPBA) 4-Carboxyphenylboronic acid (3.65 g, 22.00 mmol), ethylenediamine dihydrochloride (1.33 g, 10.00 mmol), HATU (11.40 g, 30.00 mmol) and HOAT (4.08 g, 30.00 mmol) were dissolved in DMF (40 mL) under nitrogen atmosphere and ice bath conditions
This work, along with other preclinical data, demonstrates that GHS-R1a is a promising target for the treatment of alcohol dependence
Hepatology Gastroenterology 39, 230236
Hemodynamic Profile: The net result of these actions is a significant reduction in systolic and diastolic blood pressure, heart rate, stroke volume, and total peripheral resistance, while clinically preserving renal blood flow and glomerular filtration (Mitchell et al., 2005)