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Ginsenoside compound K increases glucagon-like peptide-1 release and L-cell abundance in db/db mice through TGR5/YAP signaling

Glucagon-like peptide-1 (GLP-1) is a glucoregulatory hormone synthetized in the intestines and the brain, involved in the maintenance of energy homeostasis mainly by stimulating insulin secretion and regulation of appetite

These supplements might be somewhat helpful, but what often moves the scale are lifestyle changes

In reducing the risk of major adverse liver outcomes and HCC, large-scale observational studies and meta-analyses have demonstrated that GLP-1RA and SGLT2i exhibit comparable protective effects, with both showing significant superiority over traditional hypoglycemic agents such as DPP-4i and sulfonylureas

Huber et al (2024)

A strong comparison should connect mechanism, evidence strength, safety, access, and cost instead of only naming a winner