doi: 10.3389/fphar.2025.1656012 Received 29 June 2025 Accepted 17 September 2025 Published 30 September 2025 Volume 16 - 2025 Edited by Junmin Zhang, Lanzhou University, China Reviewed by Inamul Hasan Madar, Yenepoya (deemed to be University), India Leena Dhoble, University of Florida, United States Updates Copyright 2025 Liu, Ma, Chen, Gu, Sun and Li
Jackson JM, Blaine D, Powell-Tuck J, Korbonits M, Carey A, Elia M
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The dose escalation phase (weeks 416, depending on the specific medication) involves gradually increasing the dose according to the prescribed schedule
Wegovy continues escalating) Months 46 (Wegovy only): 1.7 mg 2.4 mg weekly maintenance dose Clinical data from the STEP 5 trial (2-year follow-up) showed that the majority of participants tolerated semaglutide well in the long term, with fewer than 4% discontinuing due to side effects
