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Statistical analysis A sample size of 361 participants per treatment arm was calculated to provide 85% power to jointly confirm the superiority of oral semaglutide (14 mg and 7 mg) vs sitagliptin 100 mg and the non-inferiority of oral semaglutide 3 mg vs sitagliptin 100 mg in reducing HbA 1c at week 26 for the trial product estimand

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It may be especially useful for those who are hesitant to use injectable medications

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indicates a reduced risk observed in the trial

Understanding how peptides work at the mechanistic level helps you choose the right approach for your specific situation