A physician-supervised plan can help answer whether the medication is appropriate, which option fits the patients risk profile, what dose should be used, how quickly the dose should increase, what side effects should be expected, when the dose should be held or adjusted, how much protein the patient should eat, how muscle can be preserved, what labs should be tracked, and what long-term maintenance should look like
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To date 6 randomised placebo-controlled trials have investigated the efficacy and safety of GLP1 agonists in early to moderately advanced PD (Table 4
[75] These enzymes act by transferring an acetyl group from their substrate protein to the ADP-ribose moiety of NAD +
