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The concern regarding how GLP-1 medications affect birth control has to do with the fact that these medications significantly impact the rate of gastric emptying after meals

Clinical trials have shown that weight loss with these medications typically ranges from 10-20% of body weight, depending on the specific agent and dosage, with tirzepatide showing the highest average weight reduction

The lowest dose of retatrutide still delivered 19% weight loss, making it nearly as effective as the highest dose of Lillys Zepbound

When To Consult A Doctor Contact your doctor if you have: Severe or persistent vomiting Severe diarrhoea Signs of dehydration, such as very low urine, dizziness, or extreme weakness Severe abdominal pain, especially if it spreads to the back Yellowing of the skin or eyes Fever with abdominal pain Inability to pass stool or gas Repeated low blood sugar episodes Sudden vision changes Palpitations or a racing heartbeat at rest Swelling of the face, lips, tongue, or throat Breathing difficulty Severe rash or itching New or worsening depression Suicidal thoughts Symptoms before planned surgery or endoscopy If you are scheduled for surgery or a procedure under anaesthesia, tell your healthcare team that you are using a GLP-1 medicine

Health effects of overweight and obesity in 195 countries over 25 years

doi: 10.1007/s11154-019-09511-1 101 ShackleyMMaYTateEWBrownAJHFrostGHanyalogluAC