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Pharmacopeia, 2019)

Compared with placebo, semaglutide increased the incidences of AEs, SAEs, and DAEs, especially DAEs, and gastrointestinal side effects accounted for the majority, particularly nausea and diarrhea, which is probably owing to the long-term gastric emptying (Wharton et al., 2022)

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By activating these pathways, GLP-1 medications may dampen the neural drive toward excessive eating episodes

Mounjaro for weight loss utilizes tirzepatide, which targets both GLP-1 and GIP receptors for potentially enhanced effectiveness