Vancomycin nephrotoxicity has been associated with high-dosage, extended duration of use, or combination therapies with other nephrotoxic drugs (Gupta 2011)
For example, when introduced via microparticle bombardment, cDNA encoding the arGST from Zea mays ( ZmBZ2 ) can complement mutations of the corresponding genes encoding arGST ( PhAN9 ) in Petunia spp., and vice versa
Preeti SS, Malik R, Bhatia S, Al Harrasi A, Rani C et al
That is the honest assessment
Warning Signs to Report Immediately Call your healthcare provider if you experience: Severe vomiting Inability to eat or drink Dizziness or fainting Severe abdominal pain Rapid weight loss Signs of dehydration Muscle weakness Never stop or start medications without medical guidance
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