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TBI was found to reduce the levels of mitochondrial antioxidants, such as glutathione, peroxiredoxin (PRX-3), thioredoxin (TRX), nicotinamide adenine dinucleotide phosphate (NADPH), superoxide dismutase (SOD), and catalase (CAT), and increase the expression of glyceraldehyde 3-phosphate dehydrogenase (GAPDH) [106]

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216,601 However, due to technical limitations and the complexity of proteins in biological systems, research on these sites lacks systematic planning, making it challenging to form conclusive research outcomes