Mean HbA1c (%) over time - baseline to week 56 Combination with metformin or metformin with sulfonylurea In a 56-week, open-label trial (NCT01885208), 813 patients with type 2 diabetes mellitus on metformin alone (49%), metformin with sulfonylurea (45%), or other (6%) were randomized to OZEMPIC 1 mg once weekly or exenatide 2 mg once weekly
The results showed a significant statistical correlation between DPP-4 inhibitors and AEs related to biliary diseases, while GLP-1 RAs exhibited strong signal intensity, suggesting a possible association with biliary diseases
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They can also be exposed by breathing air that contains sarin
As such, we anticipate that the overall number of patients that visit an REH within a given year would be high enough so that there would not be any issues with low case volumes that could undermine the reliability of this measure when used in the REH context
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