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A large study using insurance claims data found that adults aged 18 to 65 with type 2 diabetes newly prescribed GLP-1 receptor agonists had about 9 cases of ischemic optic neuropathy per 10,000 people over 18 months

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Conversely, a few studies reported high levels of vitamin B12 in the blood of patients with a worse COVID-19 outcome 48,49 potentially due to cytolysis leading to the release of intracellular B12 into the plasma and disrupted B12 clearance by the liver, which is often affected in these patients 50