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For patients taking gabapentin, genetic testing clarifies whether standard-dose semaglutide will achieve meaningful weight loss or if a higher dose or dual-compound approach (like GLP-Squared) warrants consideration

For people from specified minority ethnic groups, these thresholds are reduced by 2.5 kg/m

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Groups are often incomplete: for example, endocrine therapy (L02) excludes antigrowth hormones (listed in H01BC), while the combination of polyestradiol with "non-listed" local anaesthetics is included (L02AA)

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