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Overweight patients with NAFLD exhibited clinically significant fibrosis (stages F24) at a rate of 20.3%, while obese patients had a slightly higher prevalence at 21.6%

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We chose (EAAAK) 3 rigid helical linkers to work because we believe their rigidity allows for the separation of the protein domains and improves the functionality of individual domains 58,59 when compared to flexible linkers, which appear to be suitable for linking normally connected domains in a single genetic construct, such as antibody domains in scFvs 60

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