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In this condition of viral infection, oxidative stress is imposed by GSH depletion, occurring in two steps and following direct virus challenge of the cell membrane, without the intervention of ROS (Ciriolo et al., 1997)

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On the drug pricing front, the Trump administration brokered most-favored-nation (MFN) pricing deals with Novo Nordisk and Eli Lilly in November 2025, reducing GLP-1 prices for Medicare/Medicaid to approximately $245/month and launching a direct-to-consumer platform (TrumpRx) offering prices around $350/month ( [17] )

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