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Shungus model which builds on Martin Palls ME/CFS NO/ONOO model goes something like this: An immunological trigger or pathogen triggers the production of pro-inflammatory cytokines and the potent free radical peroxynitrite

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Currently, appendicitis is not listed as a common side effect, but it has appeared in the safety data of several large-scale clinical trials

this phenomenon demonstrates that IR may be responsible for increased cardiovascular disease risk (70)

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