Megaloblastic anemia Diminished activity of methionine synthase in vitamin B 12 deficiency inhibits the regeneration of tetrahydrofolate (THF) and traps folate in a form that is not usable by the body ( Figure 3 ), resulting in symptoms of folate deficiency even in the presence of adequate folate
Elevated serum B12 is usually asymptomatic and discovered incidentally during routine blood tests Common causes include B12 supplementation, liver disease, haematological disorders, and chronic kidney disease Symptoms such as jaundice, unexplained weight loss, or bruising suggest underlying pathology requiring investigation B12 is water-soluble with no established upper safe limit, and excess is naturally excreted by the kidneys Management focuses on identifying and treating underlying causes rather than lowering B12 levels directly Patients with persistent elevation should undergo comprehensive assessment including liver function, renal function, and haematological investigations Table of Contents What Are the Symptoms of High Vitamin B12 Levels
Vitamin B12 (Methylcobalamin or Cyanocobalamin): A vital nutrient that supports nervous system health, energy production, and red blood cell formation
Vitamins play a critical role in many bodily functions, such as boosting the immune system, improving energy levels, supporting metabolism, and keeping skin and hair healthy
A 2.5 mg dose is 1.0 mL, or 100 units on a U-100 syringe
One study showed that some patients may also start drinking more water, creating the risk of polyuria among the elderly community
