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The estrogen/progestin birth control pill greatly lowers testosterone and IGF-1 while replacing natural estrogen and progesterone with synthetic analogs, which can have negative effects in some women

As well, there are side effects that are associated with these medications, such as nausea, diarrhea, and constipation

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This mechanism positions KPV as a promising candidate for intestinal inflammation therapy, providing targeted anti-inflammatory action while avoiding the systemic immunosuppression associated with conventional treatments

S., Sharma J