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Effects of pioglitazone, a peroxisome proliferator-activated receptor gamma agonist, on the urine and urothelium of the rat

Additionally, it plays a pivotal role in the metabolism of various substances, including nutrients and drugs

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It serves as a protective mechanism to regulate the passage of substances across the BBB and prevents physiologically irrelevant molecules in the peripheral circulation from entering the brain

10.1074/jbc.M105395200 J

Glutathione plays a crucial role in protecting cells from oxidative stress, which is implicated in the pathogenesis of many diseases, including neurodegenerative disorders, cardiovascular diseases, and liver diseases