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In this trial, from randomization to week 72, TZP determinates more significant improvements versus placebo in both SBP (TZP 5.1 mmHg, placebo, 4.1 mmHg ( Figure 6A ) and DBP (TZP 3.2 mmHg, placebo 2.3 mmHg) (105) ( Figure 6B )

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doi: 10.1007/s12551-010-0041-4

In contrast, DCs under mTOR inactivation conditions favor differentiation of FOXP3 + Tregs [98]