Researchers comparing GLP-1 mono-agonism with dual GIP/GLP-1 mechanisms frequently pair Semaglutide with Tirzepatide, and with the triple GLP-1/GIP/glucagon agonist Retatrutide for head-to-head pharmacodynamic studies
& Ohta, H
Annu Rev Pharmacol Toxicol 47:14383, PMID: 17029566 Kaludercic N, Takimoto E, Nagayama T, Feng N, Lai EW, Bedja D, Chen K, Gabrielson KL, Blakely RD, Shih JC, Pacak K, Kass DA, Di Lisa F, Paolocci N (2010) Monoamine oxidase A-mediated enhanced catabolism of norepinephrine contributes to adverse remodeling and pump failure in hearts with pressure overload
Increased access to these medications may further increase public scrutiny and litigation attention surrounding their alleged risks
By now, most people have heard of Ozempic
I love serving mezze with some homemade pita bread