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Molecular recognition of ternary complexes: a new dimension in the structure-guided design of chemical degraders
Yes, many lyophilized peptides are sealed under a vacuum to ensure sterility and stability
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Current Pharmaceutical Design, 22 (8), 949-954
41 Slc3a2-dependent BCAA metabolism also has a key role in the physiological activities of Foxp3 + Treg cells, and either BCAA deprivation or SLC3A2 mutation can induce impaired activation of the mTORC1 pathway in Treg cells and inhibit the immunosuppressive function of Treg cells