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The impact of these factors is further compounded by older age, and presence of comorbidities, as well by pre-existing low muscle mass, sarcopenia, a history of weight recycling and calorie restriction [Fig

It helps transport long-chain fatty acids into the cell mitochondria, where they are burned and used as fuel

1 Our lungs also have a high amount of glutathione

Ferroptosis plays an unneglectable role in regulating the growth and proliferation of some types of tumour cells, such as lymphocytoma, ductal cell cancer of the pancreas, renal cell carcinoma (RCC) and hepatocellular carcinoma (HCC)

Overall, these findings support the gastrointestinal and hepatobiliary safety of GLP-1 receptor agonists