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In addition, we also observed lower expression of BAX and caspase 3 and higher expression of Bcl-2 in hyperplastic prostate tissues compared with normal prostate tissues, which showed that with the down-regulation of GPX3, the apoptosis level of hyperplastic prostate was inhibited at the tissue level
Sci Rep 4 , 4272 (2014)
287,288 This binding initiates typical GPCR signaling, leading to G protein activation and increased intracellular cAMP
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Each dose level is maintained for at least 4 weeks before the next increase
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