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Levels of this peptide decline with age, which is one reason it has been studied extensively in aging, skin regeneration, and wound-healing research

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doi: 10.3748/wjg.v21.i23.7142

Bone (2003) 33(1):809.10.1016/S8756-3282(03)00165-0 226 OchiaiHOkadaSSaitoAHoshiKYamashitaHTakatoTet alInhibition of insulin-like growth factor-1 (IGF-1) expression by prolonged transforming growth factor-beta1 (TGF-beta1) administration suppresses osteoblast differentiation

Results vary, but many people notice improvements in energy within 48-72 hours of their first injection