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The LEADER and SUSTAIN-6 trials demonstrated that semaglutide reduces the risk of major adverse cardiac events, including heart attack and stroke, particularly in patients with existing type 2 diabetes or cardiovascular disease

Understanding the frequency, severity, and management of these side effects is essential for providers in monitoring patients during treatment

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Possible concerns may include nausea, vomiting, diarrhea, constipation, appetite suppression, dehydration, fatigue, gallbladder concerns, blood sugar changes, excessive weight loss, and loss of lean muscle if weight drops too quickly

In the UK, hydroxocobalamin injections are prescription-only medicines and should only be administered when clinically indicated