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Following exercise or exertion, patients with ME/CFS exhibit elevated levels of pro-inflammatory cytokines in peripheral blood, accompanied by muscle fatigue, exhaustion, and cognitive impairments, indicating that mitochondrial-driven inflammatory signaling may be a potential key driver of PEM symptoms (69)

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The next step in developing SLU-PP-332 into a drug candidate will be to refine its structure, ideally making it available as a pill instead of an injection

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Lou S, Duan Y, Nie H, et al

A total of 1961 obese or overweight patients with comorbidities were enrolled