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Adverse event-related discontinuation rates were 8% among liraglutide-treated patients compared to 4% of placebo recipients [44]

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However, these risks were comparable in other instances with tirzepatide and controls (placebo, insulin, and GLP-1RA) in subgroup analyses according to tirzepatide dose (Table 2)

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Participants began at a 2 mg starting dose and stepped up roughly every four weeks toward their assigned target