Glucagon promotes hepatic fat oxidation, essentially commanding the liver to burn its stored fat
2 Majority of patients were treated with standard of care 1,2,n,o Summary of medication at baseline (N=3533) 1,2 Select CV and CKD baseline characteristics (N=3533) 1,2 n At baseline patients in FLOW were receiving standard-of-care background therapy, including a maximum tolerated label dose of a RAAS-blocking agent including an ACE inhibitor or an ARB, unless such treatment was contraindicated or not tolerated
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Activation of these receptors generates anti-inflammatory, oxidative stress-reducing and antiatherogenic effects, which support the cardioprotective and nephroprotective effects of GLP-1 agonists (Fig
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[DOI] [PubMed] [Google Scholar] 52.Klausen M.K., Jensen M.E., Mller M., Le Dous N., Jensen A.M.., Zeeman V.A., Johannsen C.F., Lee A., Thomsen G.K., Macoveanu J., et al