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Patients should be aware that this formulation may cause skin irritation, redness, or itching

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Additive effect on kidney outcomes including macroalbuminuria was also expected from AMPLITUDE-O substudy, however, additive effect of semaglutide and SGLT2i on the composite kidney outcomes without macroalbuminuria was not indicated in the FLOW substudy [50]

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However, a meta-analysis revealed significantly higher clinical pregnancy rates (OR = 1.59) and live birth rates (OR = 2.17) among patients who underwent intracytoplasmic sperm injection (ICSI) following VR [52]

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